儿少卫生与妇幼保健学系
孟秀红
发布日期
2023-06-29
浏览人数
4942


  孟秀红,医学博士,教授,博士生导师,美国约翰·霍普金斯大学(Johns Hopkins University)beat365平台和医学院访问学者,安徽省学术技术带头人后备人选。研究方向:环境与心理行为发育。近年重点研究发育关键期暴露环境内分泌干扰物对生殖和中枢神经内分泌干扰效应及其对脑和行为发育的损害效应。先后主持国家自然科学基金项目2 项、安徽省高校自然科学重大项目1项、安徽省高校自然科学重点项目1 项、安徽省自然科学基金1 项、bat365在线平台网站登录博士科研基金1项;参与国家自然科学基金重点项目2 项和青年项目1项;近年以第一(通讯)作者或合作作者发表SCI 论文19 篇,中文核心期刊多篇;荣获中华医学科技奖1 项(排名第四)和安徽省科学技术奖1 项(排名第四)。担任国家“十三五”规划教材《儿童少年卫生学》(第八版)编写秘书和人民卫生出版社高等学校教材《医学科研入门》(第一版和第二版)编委。

主持或参加科研项目及人才计划项目情况:

(1)国家自然科学基金面上项目,81773442,胎盘甲状腺素受体信号介导拟除虫菊酯诱发胎儿生长受限的机制,2018/01-2021/12,45万元,在研,主持。

(2)国家自然科学基金青年项目,81102155、肝X受体在氰戊菊酯干扰大脑皮层和海马甾体激素合成中的作用、2012/01-2014/12、22万元、已结题、主持。

(3)安徽省高等学校自然科学基金重大项目,KJ2016SD27,甲状腺激素受体信号在氰戊菊酯损害脑发育中的作用,2016/01-2018/12,20万元、已结题、主持。

(4)安徽省自然科学基金,11040606M185、双酚A致小鼠青春发动提前及其认知和行为发育损伤的脑机制、2012/01-2013/12、5万元、已结题、主持。
(5)bat365在线平台网站登录博士科研基金,XJ201115、发育关键期接触氰戊菊酯致认知和行为发育损害的脑机制、2012/01-2014/12、6万元、已结题、主持。
(6)安徽省高校自然科学研究重点项目,KJ2010A173、大脑皮层性激素合成与代谢异常在氰戊菊酯致神经行为发育损害中的作用、2011/01-2013/12、5万元、已结题、主持。

(7)国家自然科学基金重点项目,81630084,孕期维生素D缺乏与胎儿生长受限的关联及其机制研究,2017.01-2021.12,275万元,在研,参加。

(8)国家自然科学基金重点项目,81330068、孕期PAEs暴露与学龄前儿童认知损伤的出生队列研究、2014/01-2018/12、290万元、已结题、参加。
(9)国家自然科学基金青年项目,30901202、孕早期亚临床甲状腺功能减退和心理应激交互作用婴儿认知功能损伤、2010/01-2012/12、19万元、已结题、参加。
(10)安徽省学术和技术带头人后备人选,2012,医学科学。
代表性学术论文(*为通讯作者):

(1) Guo CYang YShi MXWang BLiu JJXu DX*, Meng XH(孟秀红)*. Critical time window of fenvalerate-induced fetal intrauterine growth restriction in mice. Ecotoxicol Environ Saf, 172: 186-193, 2019.  (IF:3.99)

(2) Liu JJ, Guo C, Wang B, Shi MX, Yang Y, Yu Z, Meng XH (孟秀红)*, Xu DX* . Maternal fenvalerate exposure during pregnancy impairs growth and neurobehavioral development in mouse offspring. Plos One, 13(10):e0205403, 2018.  (IF:2.766)

(3) Wang B, Liu JJ, Wang Y, Fu L, Shen R, Yu Z, Wang H, Chen YH, Zhan C, Meng XH (孟秀红)*, Xu DX*. Maternal fenvalerate exposure induces fetal intrauterine growth restriction through disrupting placental thyroid hormone receptor signaling. Toxicol Sci, 201; 157(2): 377-386, 2017.  (IF:3.880)

(4) Meng XH (孟秀红)#, Liu P#, Wang H, Zhao XF, Xu ZM, Chen GH, Xu DX*. Gender-specific impairments on cognitive and behavioral development in mice exposed to fenvalerate during puberty. Toxicol Lett, 203(3), 245-251, 2011. (IF:3.145)
(5) Meng XH (孟秀红)*, Tao FB, Wan YH, Hu Y, Wang RX. Coping as a mechanism linking stressful life events and mental health problems in adolescents. Biomed Environ Sci, 24(6), 649-655, 2011. (IF:1.154)
(6) Liu P#, Meng XH (孟秀红)#, Wang H, Ji YL, Zhao M, Zhao XF, Xu ZM, Chen YH, Zhang C, Xu DX*. Effects of pubertal fenvalerate exposure on testosterone and estradiol synthesis and the expression of androgen and estrogen receptors in the developing brain. Toxicol Lett, 201(2), 181-189, 2011. (IF:3.145)
(7) Wang H#, Meng XH (孟秀红) #, Ning H, Zhao XF, Wang Q, Liu P, Zhang H, Zhang C, Chen GH, Xu DX*. Age- and gender-dependent impairments of neurobehaviors in mice whose mothers were exposed to lipopolysaccharide during pregnancy. Toxicol Lett, 192(2), 245-251, 2010.  (IF:3.145)
(8) Wang H, Li L, Zhao M, Chen YH, Zhang ZH, Zhang C, Ji YL, Meng XH (孟秀红), Xu DX*. Melatonin alleviates lipopolysaccharide-induced placental cellular stress response in mice. J Pineal Res, 50(4), 418-426, 2011. (IF:7.304) 
(9) Ji YL, Wang H, Meng C, Zhao XF, Zhang C, Zhang Y, Zhao M, Chen YH, Meng XH (孟秀红),  Xu DX*. Melatonin alleviates cadmium-induced cellular stress and germ cell apoptosis in testes. J Pineal Res, 52(1), 71-79, 2012. (IF:7.304)
(10) Wang H, Wang Q, Zhao XF, Liu P, Meng XH (孟秀红), Yu T, Ji YL, Zhang H, Zhang C, Zhang Y, Xu DX*. Cypermethrin Exposure during Puberty Disrupts Testosterone Synthesis via Downregulating StAR in Mouse Testes. Arch Toxicol, 84(1), 53-61, 2010. (IF:5.215)
(11) Wang Z, Wang H, Xu ZM, Ji YL, Chen YH, Zhang ZH, Zhang C, Meng XH(孟秀红), Zhao M, Xu DX*. Cadmium-induced teratogenicity: association with ROS-mediated endoplasmic reticulum stress in placenta. Toxicol Appl Pharmacol, 259(2), 236-247, 2012. (IF:3.975)
(12) Zhang H, Wang H, Ji YL, Ning H, Yu T, Zhang C, Zhang Y, Zhao XF, Wang Q, Liu P, Meng XH (孟秀红), Xu DX*. Lactational fenvalerate exposure permanently impairs testicular development and spermatogenesis in mice. Toxicol Lett, 191(1), 47-56, 2009. (IF:3.145)
(13) Wang H, Wang SF, Ning H, Ji YL, Zhang C, Zhang Y, Yu T, Ma XH, Zhao XF, Wang Q, Liu P, Meng XH (孟秀红), Xu DX*. Maternal cypermethrin exposure during lactation impairs testicular development and spermatogenesis in male mouse offspring. Environ Toxicol, 26(4), 382-394, 2011. (IF:2.708)
(14) Zhang H, Wang H, Wang Q, Zhao XF, Liu P, Ji YL, Ning H, Yu T, Zhang C, Zhang Y, Meng XH (孟秀红), Xu DX*. Pubertal and early adult exposure to fenvalerate disrupts steroidogenesis and spermatogenesis in mice at adulthood. J Appl Toxicol, 30(4), 369-377, 2010. (IF:2.597)
(15) Ji YL, Wang H, Liu P, Wang Q, Zhao XF, Meng XH (孟秀红), Yu T, Zhang H, Zhang C, Zhang Y, Xu DX*. Pubertal cadmium exposure impairs testicular development and spermatogenesis via disrupting testicular testosterone synthesis in adult mice. Reprod Toxicol, 29(2), 176-183, 2010. (IF:3.141)
(16) Zhang C, Chen X, Zhu RM, Zhang Y, Yu T, Wang H, Zhao H, Zhao M, Ji YL, Chen YH, Meng XH (孟秀红), Wei W, Xu DX*. Endoplasmic reticulum stress is involved in hepatic SREBP-1c activation and lipid accumulation in fructose-fed mice. Toxicol Lett, 212(3), 229-240, 2012. (IF:3.145)
(17) Wang H, Ji YL, Wang Q, Zhao XF, Ning H, Liu P, Zhang C, Yu T, Zhang Y, Meng XH (孟秀红), Xu DX*. Maternal lead exposure during lactation persistently impairs testicular development and steroidogenesis in male offspring. J Appl Toxicol, 33(12), 1384-13942, 2013. (IF:2.597)
(18) Ji YL, Wang H, Zhao XF, Wang Q, Zhang C, Zhang Y, Zhao M, Chen YH, Meng XH(孟秀红), Xu DX*. Crosstalk between endoplasmic reticulum stress and mitochondrial pathway mediates cadmium-induced germ cell apoptosis in testes. Toxicol Sci, 124(2), 446-459, 2011. (IF:4.328)
(19) Zhang C,Chen X,Zhu RM,Zhang Y,Yu T,Wang H,Zhao H,Zhao M,Ji YL,Chen YH, Meng XH (孟秀红),Wei W, Xu DX*. Endoplasmic reticulum stress is involved in hepatic SREBP-1c activation and lipid accumulation in fructose-fed mice. Toxicol Lett, 212(3), 229-240, 2012. (IF:3.145)

(20) 孟秀红,陶芳标,黄朝辉,胡传来,万宇辉. 多维学生生活满意度量表在中国青少年中的应用.中国心理卫生杂志, 24(8): 613-618, 2010.

(21) 孟秀红,黄朝辉,孙莹,陶芳标,万宇辉,许韶君. 应对方式对生活满意度和抑郁、焦虑症状关联的中介效应. 吉林大学学报 (医学版), 36(5): 989-993, 2010.

(22) 孟秀红,邢超,何成森,陶芳标. 大学生自我和谐与父母教养方式的相关性分析. 中国学校卫生, 31(5): 563-565, 2010.

(23) 孟秀红,郝加虎,陶芳标,黄锟,孙莹,朱鹏. 从本科医学教育标准探讨人才培养模式创新. 医学教育探索, 9(1): 12-17, 2010.

省级以上学术奖励:
(1) 徐德祥,王华,姬艳丽,孟秀红,张程,陈远华,赵梅. 生命不同阶段暴露环境内分泌干扰物对男(雄)性生殖发育的损害效应,中华医学会,中华医学科技奖,三等奖,2014.
(2) 徐德祥,姬艳丽,王华,孟秀红,张立. 几种环境化学物的男(雄)性生殖毒性和内分泌干扰效应,安徽省科技厅,安徽省科学技术奖,二等奖,2014.
(3) 孟秀红,徐德祥,刘萍. Gender-specific impairments on cognitive and behavioral development in mice exposed to fenvalerate during puberty,安徽省科技厅,安徽省自然科学优秀学术论文,三等奖,2013. 
(4) 刘萍,徐德祥,孟秀红. Effects of pubertal fenvalerate exposure on testosterone and estradiol synthesis and the expression of androgen and estrogen receptors in the developing brain,安徽省科技厅,安徽省自然科学优秀学术论文,二等奖,2013.
(5) Wang H, Li L, Zhao M, Chen YH, Zhang ZH, Zhang C, Ji YL, Meng XH(孟秀红), Xu DX. Melatonin alleviates lipopolysaccharide-induced placental cellular stress response in mice,安徽省科技厅,安徽省自然科学优秀学术论文,一等奖,2012.